Tuesday, October 30, 2012

Hypertension and Anabolic Steroids: A New Pathway?


Here is a great new science piece on AS and Hypertension from our good friend Pat Arnold. This is a must read for gear users!

Hypertension and Anabolic Steroids: A New Pathway?
October 30, 2012 ,
by Patrick Arnold

People familiar with the use of anabolic steroids know that water retention and hypertension (high blood pressure) are potential side effects. This is due to the fact that all androgenic hormones have the capacity to cause some sodium retention (and hence water retention) through direct action via androgen receptors in the kidneys. Furthermore, anabolic steroids that are estrogenic or can convert to estrogens can cause even more sodium retention via additional interaction with renal (kidney) estrogen receptors. So it’s often thought that an anabolic steroids propensity for water retention is related to its potency both as an androgen and as an estrogen (manifested via aromatization to estrogenic metabolites).